Abstract:
This paper proposes a novel method for genome editing using cellular
automata evolutions of adjoints of Adenine, Thymine, Guanine, and Cytosine. The
adjoints of the given a genome sequence are the characteristic binary string
sequences. For example, the adjoint of Adenine of a given genome sequence is a
binary string consisting of 0’s and 1’s where 1’s corresponds to the presence of
Adenine in the genome sequence. So, one can have four adjoint sequences of Adenine,
Thymine, Guanine, and Cytosine corresponding to a given genome sequence. Onedimensional
three neighborhood binary value cellular automata rules can be applied
to an adjoint sequence and the desired number of evolutions could be obtained. This
rule is defined by a linear Boolean function and one can have 256 such linear
Boolean functions. Genome editing is carried out by superimposing the evolved
adjoint sequence on the original genome sequence or on its successive evolutions. In
this manner, one can have four ways of genome editing using four adjoint sequences
and evolutions.
Keywords:
Genome Editing,Cellular Automata,Evolutions of Adjoints,Linear Boolean functions,
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